Journal reference: Nishimura K, Sugiyama D, Kogata Y, Tsuji G, Nakazawa T, Kawano S, et al. Meta-analysis: diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis. Ann Intern Med 2007; 146(11): 797-808; and others.
Published: 5 June 2007
|There is no role for diagnostic rheumatoid factor (RF) testing in someone without inflammatory arthritis.
An elevated RF increases the odds of rheumatoid arthritis about 5-fold. The post-test risk, however, depends on the pre-test risk.