Feb 19 2016
Journal reference: Cesarone MR, Belcaro G, Nicolaides AN, et al. Venous thrombosis from air travel: the LONFLIT3 study–prevention with aspirin vs low-molecular-weight heparin (LMWH) in high-risk subjects: a randomized trial. Angiology 2002 Jan-Feb;53(1):1-6.
Link: http://www.ncbi.nlm.nih.gov/pubmed/11863301
Published: Jan 2002
 Evidence cookie says… |
It is unclear whether aspirin is effective as DVT prophylaxis for high risk long-haul travellers.
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Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1687
Oct 30 2015
Journal reference: Hill EM, Sky K, Sit M, Collamer A, Higgs J. Does starting allopurinol prolong acute treated gout? A randomized clinical trial. J Clin Rheumatol 2015;21(3):120-5.
Link: http://www.ncbi.nlm.nih.gov/pubmed/25807090
Published: April 2015
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Evidence cookie says… |
It is unclear what effect starting allopurinol in acute gout has on symptoms, due to the lack of good evidence.
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Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1683
Sep 04 2015
Journal reference: Olaussen M, Holmedal O, Lindbaek M, Brage S, Solvang H. Treating lateral epicondylitis with corticosteroid injections or non-electrotherapeutical physiotherapy: a systematic review. BMJ Open 2013;3(10):e003564
Link: http://dx.doi.org/10.1136/bmjopen-2013-003564
Published: 29 October 2013
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Evidence cookie says… |
Corticosteroid injections should be generally avoided for tennis elbow (lateral epicondylitis).
They are associated with:
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Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1677
Jul 10 2015
Journal reference: Timmer A, Günther J, E Motschall, Rücker G, Antes G, Kern WV. Pelargonium sidoides extract for acute respiratory tract infections Treating. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No .: CD006323.
Link: http://dx.doi.org/10.1002/14651858.CD006323.pub3
Published: 22 October 2013
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Evidence cookie says… |
There exists only very-low quality evidence of the effect of Pelargonium sidoides extract (Kaloba ®, Umckaloabo) on the common cold.
This precludes it from being recommended routinely in primary care settings. |
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1669
May 15 2015
Journal reference: Williams CM, Maher CG, Latimer J, McLachlan AJ, Hancock MJ, Day RO, et al. Efficacy of paracetamol for acute low-back pain: a double-blind, randomised controlled trial. Lancet 2014;384(9954):1586-96.
Link: http://dx.doi.org/10.1016/S0140-6736(14)60805-9
Published: 1 November 2014
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Evidence cookie says… |
Paracetamol (regular and intermittent dosing) does not have an effect on time to recovery for acute low-back pain in the general practice setting.
Recommendations for the use of regular adult dosing of paracetamol should be reconsidered. The median time to recovery from acute low-back pain is 16-17 days. |
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1664
Mar 13 2015
Journal reference: Fox MJ, Ahuja KD, Robertson IK, Ball MJ, Eri RD. Can probiotic yogurt prevent diarrhoea in children on antibiotics? A double-blind, randomised, placebo-controlled study. BMJ Open 2015;5(1): e006474. DOI: 10.1136/bmjopen-2014-006474
Link: http://dx.doi.org/10.1136/bmjopen-2014-006474
Published: 14 January 2015
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Evidence cookie says… |
Probiotic yoghurt appears to reduce the incidence of diarrhoea in children receiving antibiotics in general practice settings.
The dose was 2 x 100 g tubs of Vaalia-brand yoghurt daily during the antibiotic course of treatment. This is a reasonable preventive intervention to advise – especially for children who enjoy yoghurt. |
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1658
Nov 07 2014
Journal reference: Rapaport MH, Nierenberg AA, Howland R, Dording C, Schettler PJ, Mischoulon D. The treatment of minor depression with St. John’s Wort or citalopram: failure to show benefit over placebo. Journal of Psychiatric Research 2011; 45(7): 931-941. DOI: 10.1016/j.jpsychires.2011.05.001
Link: http://dx.doi.org/10.1016/j.jpsychires.2011.05.001
Published: July 2011
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Evidence cookie says… |
St John’s wort is probably ineffective for minor depression.
Of the little evidence available, there appears to be no benefit over placebo, and evidence of side-effects. |
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1654
Sep 05 2014
Journal reference: Derry CJ, Derry S, Moore RA. Caffeine as an analgesic adjuvant for acute pain in adults. Cochrane Database of Systematic Reviews 2012, Issue 3. Art. No.: CD009281.
Link: http://dx.doi.org/10.1002/14651858.CD009281.pub2
Published: 14 March 2012
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Evidence cookie says… |
Oral caffeine (100 mg) as a single dose may have a modest effect on acute pain (including migraine) when used as an adjuvant to oral analgesia (including paracetamol).
There are significant uncertainties in the evidence-base and this finding should be treated cautiously. There is an absence of evidence for repeated doses of caffeine. |
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1646
Jul 11 2014
Journal reference: Taylor JA, Webber W, Standish L, Quinn H, Goesling J, McGann M, Calabrese C. Efficacy and safety of echinacea in treating upper respiratory tract infections in children: a randomized controlled trial. JAMA 2003; 290(21): 2824-2830
Link: http://dx.doi.org/10.1001/jama.290.21.2824
Published: 3 December 2003
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Evidence cookie says… |
Echinacea does not appear to be an effective treatment for the common cold in children.
Side-effects (such as rash and allergic reactions) can occur and the UK regulatory body (MHRA) recommends against its use in children under 12 years. |
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1638
May 16 2014
Journal reference: de Bastos M, Stegeman BH, Rosendaal FR, Van Hylckama Vlieg A, Helmerhorst FM, Stijnen T, Dekkers OM. Combined oral contraceptives: venous thrombosis. Cochrane Database of Systematic Reviews 2014, Issue 3. Art. No.: CD010813. DOI: 10.1002/14651858.CD010813.pub2.
Link: http://dx.doi.org/10.1002/14651858.CD010813.pub2
Published: 3 March 2014
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Evidence cookie says… |
Combined oral contraceptives containing drospirenone as compared to levonorgestrel are associated with twice the risk of venous thrombosis (and about 4x the risk of non-use).
However, the absolute risk difference is small: less than 0.1% increased probability of venous thrombosis per year (NNH ≈ 1500). |
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1615
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