Category: Neurology

Oct 19 2018

The combination of magnesium, riboflavin, and coenzyme Q10 for migraine prophylaxis

Gaul et al. J Headache Pain 2015;16:516.
The evidence for combination magnesium, riboflavin, and CoQ10 is at best equivocal for migraine prophylaxis

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1752

Jun 25 2018

Do statins prevent dementia?

McGuinness et al. Cochrane database of systematic reviews 2016 Jan 4(1):CD003160
Statins should not be used as a prophylaxis against dementia, as the only indication. The limited evidence from high quality randomised trials suggests no effect.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1742

Sep 05 2014

Does caffeine help with migraines?

Derry et al. Cochrane Database of Syst Rev 2012, Issue 3. Art. No.: CD009281
Oral caffeine as a single dose may have a modest effect on acute pain when used as an adjuvant to oral analgesia.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1646

Apr 13 2011

Proton pump inhibitors with clopidogrel

van Boxel OS, et al. Cardiovascular and gastrointestinal outcomes in clopidogrel users on proton pump inhibitors: results of a large Dutch cohort study. Am J Gastroenterol 2010; 105: 2430–6
Concurrent proton pump inhibitors may increase the risk of cardiovascular outcomes in patients taking clopidogrel.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1322

Apr 06 2011

Deaths after chiropractic upper cervical spine manipulation

Ernst E. Deaths after chiropractic: a review of published cases. Int J Clin Pract, July 2010; 64(8): 1162-5
Chiropractic, specifically, high-velocity, short-lever thrusts of the upper spine with rotation is associated with numerous deaths.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1312

Feb 28 2011

B-vitamins and omega-3 fatty acids on vascular disease

Galan P, et al. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a RCT. BMJ 2010; 341:c6273
B-vitamin and low dose omega-3 fatty acid supplements are not associated with better vascular outcomes in people with ischaemic heart disease and stroke.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=993

Jan 10 2011

Tricyclic antidepressants and headaches

Jackson JL, et al. Tricyclic antidepressants and headaches: systematic review and meta-analysis. BMJ 2010;341:c5222
Tricyclic antidepressants are possibly/probably effective in reducing the frequency and intensity of migraine and tension-type headaches.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=743