Category: Meta-analysis

Milk thistle for chronic hepatitis B

Rambaldi et al. Cochrane database Syst Rev 2007 Oct 17(4):CD003620
Milk thistle products cannot be recommended for chronic hepatitis B. Only limited research evidence of unclear/poor quality exists.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1703

Corticosteroid injections for tennis elbow

Olaussen et al. BMJ Open 2013;3(10):e003564
Corticosteroid injections should generally be avoided for tennis elbow (lateral epicondylitis).

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1677

Pelargonium sidoides extract (Kaloba (R)) for the common cold

Timmer et al. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No .: CD006323.
There exists only very-low quality evidence of the effect of Pelargonium sidoides extract on the common cold.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1669

Does caffeine help with migraines?

Derry et al. Cochrane Database of Syst Rev 2012, Issue 3. Art. No.: CD009281
Oral caffeine as a single dose may have a modest effect on acute pain when used as an adjuvant to oral analgesia.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1646

Newer oral contraceptives and risk of venous thrombosis

de Bastos M, et al. Cochrane Database of Syst Rev 2014, Issue 3. Art. No.: CD010813
cOCPs containing drospirenone as compared to levonorgestrel are associated with twice the risk of venous thrombosis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1615

Diagnostic utility of rheumatoid factor in low risk population

Nishimura K, et al. Ann Intern Med 2007; 146(11): 797-808
There is no role for diagnostic rheumatoid factor (RF) testing in someone without inflammatory arthritis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1619

Do calcium supplements increase the risk of myocardial infarction?

Bolland M, et al. BMJ 2010; 341: c3691
Calcium supplements may increase the risk of myocardial infarction, but, there is substantial uncertainty in the estimate.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1592

Zinc for the common cold

Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD001364
Zinc administered within 24 hours of the symptoms of a common cold is associated with favourable outcomes but with some side-effects.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1393

Statins in primary prevention and all-cause mortality

Ray KK, et al. Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 RCTs… Archives of Internal Medicine, 2010; 170(12): 1024-31 Statins were not associated with a benefit to all-cause mortality in a primary prevention setting.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1341

Cannabis use and earlier onset of psychosis

Large M, et al. Cannabis use and earlier onset of psychosis. Arch Gen Psychiatry 2011: published online 7 February 2011
Cannabis may be causally related to psychotic illness but the evidence remains unclear.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1280

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