Tag: pain

Palmitoylethanolamide (PEA) as treatment for knee osteoarthritis pain

Steels E, et al. Inflammopharmacology 2019 Jun;27(3):475-85.
Palmitoylethanolamide (PEA) cannot be recommended as a routine therapy for knee osteoarthritis in Australian primary care,

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1787

Duloxetine as treatment for knee osteoarthritis pain

Osani et al. Korean J Intern Med 2019 Mar 15
Duloxetine (60-120 mg daily) appears to have a small to moderate beneficial effect on knee osteoarthritis pain and function at 3 months, compared to placebo.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1782

The combination of magnesium, riboflavin, and coenzyme Q10 for migraine prophylaxis

Gaul et al. J Headache Pain 2015;16:516.
The evidence for combination magnesium, riboflavin, and CoQ10 is at best equivocal for migraine prophylaxis

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1752

Do oral sweets reduce injection pain in children?

Harrison et al. Cochrane database of systematic reviews 2015 May 5(5):CD008408
The effect of oral sweets on injection pain in children is unclear. Much of the data were from small studies with conflicting results. There is better evidence for other approaches (e.g., distraction).

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1733

Sterile water injections for acute low back pain

Cui JZ, et al. Braz J Med Biol Res 2016 Mar;49(3)
Sterile water injections are of uncertain value in acute low back pain. It may have a role in patients who consent after being informed to its uncertain value.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1700

Does co-enzyme Q10 reduce statin-related muscle pain?

Banach et al. Mayo Clin Proc 2015 Jan;90(1):24-34.
The effect of CoQ10 on muscle pain in people on statin therapy is uncertain with the evidence limited and inconsistent. CoQ10 cannot be recommended as a matter of routine supplementation to prevent muscle pain in people taking statins.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1696

Starting allopurinol in acute gout

Hill et al. J Clin Rheumatol 2015;21(3):120-5.
It is unclear what effect starting allopurinol in acute has on symptoms, due to the lack of good evidence. It may be preferable to avoid starting allopurinol in an acute attack, but this should not be a dogmatic stance.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1683

Corticosteroid injections for tennis elbow

Olaussen et al. BMJ Open 2013;3(10):e003564
Corticosteroid injections should generally be avoided for tennis elbow (lateral epicondylitis).

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1677

Paracetamol for acute low-back pain

Williams et al. Lancet 2014;384(9954):1586-96.
Paracetamol does not have an effect on time to recovery for acute low-back pain in the general practice setting.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1664

Does caffeine help with migraines?

Derry et al. Cochrane Database of Syst Rev 2012, Issue 3. Art. No.: CD009281
Oral caffeine as a single dose may have a modest effect on acute pain when used as an adjuvant to oral analgesia.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1646

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