Jun 22 2011
Connolly SJ, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361:1139-1151
Dabigatran (Pradaxa) is non-inferior to warfarin for the prevention of strokes or systemic embolism, in non-valvular atrial fibrillation.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1443
Feb 07 2011
Tähtinen PA, et al. A placebo-controlled trial of antimicrobial treatment for acute otitis media. N Engl J Med 2011; 364: 116-26
Children aged 6-35 months with acute otitis media may benefit from amoxicillin-clavulanate but at the cost of adverse events.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1065
Feb 02 2011
Matchar DB, et al. Effect of home testing of INR on clinical events. N Engl J Med 2010;363:1608-20
Home INR self-testing does not appear to improve or worsen strokes, major bleeds or death when compared to high quality practice based management of anticoagulation.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=282
Jan 12 2011
Zoungas S, et al. Severe hypoglycemia and risk of vascular events and death. N Engl J Med 2010;363:1410-8
Severe hypoglycaemia is strongly associated with increased risk of vascular events and death (~ 350% ↑ risk).
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=206
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