Category: Prevention

Feb 27 2020

N95 respirators vs surgical masks to prevent transmission of respiratory tract infections to staff in primary care

Radonovich et al. JAMA 2019 Sep 3;322(9):824-33
The advantage of N95 respirators over surgical masks in controlled settings were not demonstrated in preventing staff influenza infection in routine primary care.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1791

Jun 25 2018

Do statins prevent dementia?

McGuinness et al. Cochrane database of systematic reviews 2016 Jan 4(1):CD003160
Statins should not be used as a prophylaxis against dementia, as the only indication. The limited evidence from high quality randomised trials suggests no effect.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1742

Apr 30 2018

Does vitamin B3 (nicotinamide) prevent non-melanoma skin cancer?

Chen AC, et al. NEJM 2015 Oct 22;373(17):1618-26
Nicotinamide (vitamin B3) has a small-modest effect as prophylaxis against non-melanoma skin cancers

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1737

Aug 31 2017

Do vitamin D supplements reduce falls in older people living in the community?

Bolland et al. Lancet Diabetes Endocrinol 2014 Jul;2(7):573-80
The beneficial effect of vitamin D on falls in otherwise well community-dwelling people is likely to be small, if it exists at all. Its routine preventive use cannot be justified on the evidence.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1724

Aug 08 2016

Does co-enzyme Q10 reduce statin-related muscle pain?

Banach et al. Mayo Clin Proc 2015 Jan;90(1):24-34.
The effect of CoQ10 on muscle pain in people on statin therapy is uncertain with the evidence limited and inconsistent. CoQ10 cannot be recommended as a matter of routine supplementation to prevent muscle pain in people taking statins.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1696

Mar 15 2013

Do calcium supplements increase the risk of myocardial infarction?

Bolland M, et al. BMJ 2010; 341: c3691
Calcium supplements may increase the risk of myocardial infarction, but, there is substantial uncertainty in the estimate.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1592

Jun 22 2011

Dabigatran versus warfarin for atrial fibrillation

Connolly SJ, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361:1139-1151
Dabigatran (Pradaxa) is non-inferior to warfarin for the prevention of strokes or systemic embolism, in non-valvular atrial fibrillation.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1443

Apr 20 2011

Statins in primary prevention and all-cause mortality

Ray KK, et al. Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 RCTs… Archives of Internal Medicine, 2010; 170(12): 1024-31 Statins were not associated with a benefit to all-cause mortality in a primary prevention setting.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1341

Mar 02 2011

DHA on maternal depression and neurodevelopment

Makrides M, et al. Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trial. JAMA. 2010; 304(15): 1675-1683
DHA supplements in the later half of pregnancy are not associated with improvements in maternal depression or infant neurodevelopment.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=989

Feb 28 2011

B-vitamins and omega-3 fatty acids on vascular disease

Galan P, et al. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a RCT. BMJ 2010; 341:c6273
B-vitamin and low dose omega-3 fatty acid supplements are not associated with better vascular outcomes in people with ischaemic heart disease and stroke.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=993

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