Category: Rheumatology

Oct 11 2019

Palmitoylethanolamide (PEA) as treatment for knee osteoarthritis pain

Steels E, et al. Inflammopharmacology 2019 Jun;27(3):475-85.
Palmitoylethanolamide (PEA) cannot be recommended as a routine therapy for knee osteoarthritis in Australian primary care,

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1787

Jul 12 2019

Duloxetine as treatment for knee osteoarthritis pain

Osani et al. Korean J Intern Med 2019 Mar 15
Duloxetine (60-120 mg daily) appears to have a small to moderate beneficial effect on knee osteoarthritis pain and function at 3 months, compared to placebo.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1782

Aug 21 2018

Is oral orphenadrine beneficial for acute low back pain?

Friedman et al. Ann Emerg Med 2018 Mar;71(3):348-56 e5
Orphenadrine provides no benefit when used in addition to naproxen for acute low back pain

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1747

Aug 31 2017

Do vitamin D supplements reduce falls in older people living in the community?

Bolland et al. Lancet Diabetes Endocrinol 2014 Jul;2(7):573-80
The beneficial effect of vitamin D on falls in otherwise well community-dwelling people is likely to be small, if it exists at all. Its routine preventive use cannot be justified on the evidence.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1724

Oct 10 2016

Sterile water injections for acute low back pain

Cui JZ, et al. Braz J Med Biol Res 2016 Mar;49(3)
Sterile water injections are of uncertain value in acute low back pain. It may have a role in patients who consent after being informed to its uncertain value.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1700

Aug 08 2016

Does co-enzyme Q10 reduce statin-related muscle pain?

Banach et al. Mayo Clin Proc 2015 Jan;90(1):24-34.
The effect of CoQ10 on muscle pain in people on statin therapy is uncertain with the evidence limited and inconsistent. CoQ10 cannot be recommended as a matter of routine supplementation to prevent muscle pain in people taking statins.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1696

Oct 30 2015

Starting allopurinol in acute gout

Hill et al. J Clin Rheumatol 2015;21(3):120-5.
It is unclear what effect starting allopurinol in acute has on symptoms, due to the lack of good evidence. It may be preferable to avoid starting allopurinol in an acute attack, but this should not be a dogmatic stance.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1683

Sep 04 2015

Corticosteroid injections for tennis elbow

Olaussen et al. BMJ Open 2013;3(10):e003564
Corticosteroid injections should generally be avoided for tennis elbow (lateral epicondylitis).

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1677

May 15 2015

Paracetamol for acute low-back pain

Williams et al. Lancet 2014;384(9954):1586-96.
Paracetamol does not have an effect on time to recovery for acute low-back pain in the general practice setting.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1664

Apr 16 2014

Diagnostic utility of rheumatoid factor in low risk population

Nishimura K, et al. Ann Intern Med 2007; 146(11): 797-808
There is no role for diagnostic rheumatoid factor (RF) testing in someone without inflammatory arthritis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1619

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