Aug 08 2016
Banach et al. Mayo Clin Proc 2015 Jan;90(1):24-34.
The effect of CoQ10 on muscle pain in people on statin therapy is uncertain with the evidence limited and inconsistent. CoQ10 cannot be recommended as a matter of routine supplementation to prevent muscle pain in people taking statins.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1696
Jun 14 2016
Zheng et al. J Clin Psychopharmacol 2015 Oct;35(5):499-509.
The effect of metformin on cardiovascular disease in people living without diabetes on long-term antipsychotic medication is unknown.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1693
Nov 08 2013
Tonelli M, et al. CMAJ 2011; 183(16): E1189-E1202
Statins appear to have a (small) cardiovascular benefit, even in individuals at low CVD risk.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1607
Mar 15 2013
Bolland M, et al. BMJ 2010; 341: c3691
Calcium supplements may increase the risk of myocardial infarction, but, there is substantial uncertainty in the estimate.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1592
Jun 22 2011
Connolly SJ, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361:1139-1151
Dabigatran (Pradaxa) is non-inferior to warfarin for the prevention of strokes or systemic embolism, in non-valvular atrial fibrillation.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1443
Apr 20 2011
Ray KK, et al. Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 RCTs… Archives of Internal Medicine, 2010; 170(12): 1024-31 Statins were not associated with a benefit to all-cause mortality in a primary prevention setting.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1341
Apr 13 2011
van Boxel OS, et al. Cardiovascular and gastrointestinal outcomes in clopidogrel users on proton pump inhibitors: results of a large Dutch cohort study. Am J Gastroenterol 2010; 105: 2430–6
Concurrent proton pump inhibitors may increase the risk of cardiovascular outcomes in patients taking clopidogrel.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1322
Mar 18 2011
Myers MG, et al. Conventional versus automated measurement of blood pressure in primary care patients with systolic hypertension: randomised parallel design controlled trial. BMJ 2011; 342: d286
Automated BP measurement is significantly closer to waking ambulatory BP than conventional manual measurement.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1229
Mar 14 2011
Ogawa T, et al. Outcomes of chest compression only CPR versus conventional CPR conducted by lay people… BMJ 2011; 342: c7106
Conventional CPR may be associated with better rates of survival than chest compression only CPR when conducted by lay people in out of hospital arrests.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1116
Mar 07 2011
Trelle S, et al. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ 2011; 342:c7086
Non-steroidal anti-inflammatory drugs (NSAIDs) appear to be associated with increased cardiovascular risks.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1173
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