Category: Complementary/Alternative

Palmitoylethanolamide (PEA) as treatment for knee osteoarthritis pain

Steels E, et al. Inflammopharmacology 2019 Jun;27(3):475-85.
Palmitoylethanolamide (PEA) cannot be recommended as a routine therapy for knee osteoarthritis in Australian primary care,

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1787

The combination of magnesium, riboflavin, and coenzyme Q10 for migraine prophylaxis

Gaul et al. J Headache Pain 2015;16:516.
The evidence for combination magnesium, riboflavin, and CoQ10 is at best equivocal for migraine prophylaxis

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1752

Milk thistle for chronic hepatitis B

Rambaldi et al. Cochrane database Syst Rev 2007 Oct 17(4):CD003620
Milk thistle products cannot be recommended for chronic hepatitis B. Only limited research evidence of unclear/poor quality exists.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1703

Does co-enzyme Q10 reduce statin-related muscle pain?

Banach et al. Mayo Clin Proc 2015 Jan;90(1):24-34.
The effect of CoQ10 on muscle pain in people on statin therapy is uncertain with the evidence limited and inconsistent. CoQ10 cannot be recommended as a matter of routine supplementation to prevent muscle pain in people taking statins.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1696

Pelargonium sidoides extract (Kaloba (R)) for the common cold

Timmer et al. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No .: CD006323.
There exists only very-low quality evidence of the effect of Pelargonium sidoides extract on the common cold.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1669

Yoghurt to prevent antibiotic-associated diarrhoea in children

Fox MJ, et al. BMJ Open 2015;5(1): e006474
Probiotic yoghurt appears to reduce the incidence of diarrhoea in children receiving antibiotics in general practice settings.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1658

St John’s wort for minor depression

Rapaport MH, et al. Journal of Psychiatric Research 2011; 45(7): 931-941
St John’s wort is probably ineffective for minor depression.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1654

Does caffeine help with migraines?

Derry et al. Cochrane Database of Syst Rev 2012, Issue 3. Art. No.: CD009281
Oral caffeine as a single dose may have a modest effect on acute pain when used as an adjuvant to oral analgesia.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1646

Echinacea and the common cold in children

Taylor JA, et al. JAMA 2003; 290(21): 2824-30
Echinacea does not appear to be an effective treatment for the common cold in children.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1638

Does zinc reduce the symptoms of the common cold?

Science M, Johnstone J, Roth DE, Guyatt G, Loeb M. CMAJ 2012; 184(10): E551-E561
Oral zinc reduces the duration of cold symptoms in adults, but at the cost of side-effects.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1599

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