Author's posts
Parker C, Coupland C, Hippisley-Cox J. Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ 2010;341:c4245.
Antipsychotic drugs are associated with a 32% increased risk of venous thromboembolism.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=191
Rothwell PM, et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011; 377(9759): 31-41
Daily aspirin (≥ 75 mg) taken by participants in cardiovascular studies reduced the risk of cancer death.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=723
Athyros VG, et al. Safety and efficacy of long-term statin treatment for cardiovascular events in patients with CHD and abnormal LFTs in GREACE Study: a post-hoc analysis. Lancet 2010; 376: 1916–22
Statin are effective and safe in patients with established coronary heart disease but with mild-to-moderate abnormal liver function tests.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=686
Tibballs J, Watson T. Symptoms and signs differentiating croup and epiglottitis. Journal of Paediatrics and Child Health. (2010) 10.1111/j.1440-1754.2010.01892.x
Cough and drooling can be helpful in differentiating croup and epiglottitis in children with acute stridor.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=562
Bangalore S, et al. Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials. Lancet Oncol (2010)
Antihypertensive drugs do not appear to increase cancer risk or cancer-related deaths.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=549
Tähtinen PA, et al. A placebo-controlled trial of antimicrobial treatment for acute otitis media. N Engl J Med 2011; 364: 116-26
Children aged 6-35 months with acute otitis media may benefit from amoxicillin-clavulanate but at the cost of adverse events.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1065
Vickers AJ, et al. PSA concentration at age 60 and death or metastasis from prostate cancer: case-control study. BMJ 2010;341:c4521
Men aged 60 years with a PSA < 1.0 ng/mL have less than a 0.5% risk of prostate cancer metastasis or prostate cancer death by age 85.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=289
Matchar DB, et al. Effect of home testing of INR on clinical events. N Engl J Med 2010;363:1608-20
Home INR self-testing does not appear to improve or worsen strokes, major bleeds or death when compared to high quality practice based management of anticoagulation.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=282
Wandel S, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 2010;341:c4675
Glucosamine, chondroitin and their combination do not improve pain or reduce joint space loss in osteoarthritis of the hip or knee.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=270
Spurling GK, et al. Information from pharmaceutical companies and the quality, quantity and cost of physicians’ prescribing: a systematic review. PLoS Med, 2010; 7(10)
Exposure does not improve prescribing quality, reduce prescribing frequency or reduce prescribing costs.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=265
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