Category: Oncology

Diagnostic x-ray and ultrasound and childhood cancer

Rajaraman P, et al. Early life exposure to diagnostic radiation and ultrasound scans and risk of childhood cancer… BMJ 2011; 342: d472
The excess risk of childhood cancer from diagnostic imaging in utero and early infancy remains unclear.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1295

HRT and breast cancer incidence and mortality

Chlebowski R, et al. Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA. 2010; 304 (15):1684-1692
Combined oestrogen and progestin HRT is associated with increased risk of invasive breast cancer, node-positivity, and all cause mortality.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1062

Daily aspirin on long-term risk of death due to cancer

Rothwell PM, et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011; 377(9759): 31-41
Daily aspirin (≥ 75 mg) taken by participants in cardiovascular studies reduced the risk of cancer death.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=723

Antihypertensive drugs and the risk of cancer

Bangalore S, et al. Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials. Lancet Oncol (2010)
Antihypertensive drugs do not appear to increase cancer risk or cancer-related deaths.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=549

PSA at age 60 and death or metastasis from prostate cancer

Vickers AJ, et al. PSA concentration at age 60 and death or metastasis from prostate cancer: case-control study. BMJ 2010;341:c4521
Men aged 60 years with a PSA < 1.0 ng/mL have less than a 0.5% risk of prostate cancer metastasis or prostate cancer death by age 85.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=289