Category: Clinical domain

Diagnostic utility of rheumatoid factor in low risk population

Nishimura K, et al. Ann Intern Med 2007; 146(11): 797-808
There is no role for diagnostic rheumatoid factor (RF) testing in someone without inflammatory arthritis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1619

Mediterranean diets in type 2 diabetes

Ajala O, et al. Am J Clin Nutr 2013; 97(3): 505-516
The Mediterranean diet appears to be as good as other diets at improving glycaemic control in patients with type 2 diabetes.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1610

Are statins effective for primary prevention in people with low cardiovascular risk?

Tonelli M, et al. CMAJ 2011; 183(16): E1189-E1202
Statins appear to have a (small) cardiovascular benefit, even in individuals at low CVD risk.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1607

Is folate effective for methotrexate side effects?

Shea B, et al. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD000951
Low dose folic acid (≤ 7 mg/week) substantially reduces the likelihood of certain side-effects of methotrexate in patients with rheumatoid arthritis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1603

Does zinc reduce the symptoms of the common cold?

Science M, Johnstone J, Roth DE, Guyatt G, Loeb M. CMAJ 2012; 184(10): E551-E561
Oral zinc reduces the duration of cold symptoms in adults, but at the cost of side-effects.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1599

Is yoghurt helpful for antibiotic-associated diarrhoea?

Conway S, Hart A, Clark A, Harvey I. BJGP 2007; 57(545): 953-959
Yoghurt eaters in this study might have suffered less antibiotic-associated diarrhoea as compared to those who ate no yoghurt.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1595

Do calcium supplements increase the risk of myocardial infarction?

Bolland M, et al. BMJ 2010; 341: c3691
Calcium supplements may increase the risk of myocardial infarction, but, there is substantial uncertainty in the estimate.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1592

Is glucosamine effective for osteoarthritis pain?

Wandel S, Jüni P, Tendal B, et al. BMJ 2010; 341: c4675
Glucosamine does not appear to be effective for knee or hip osteoarthritis pain.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1588

Can exercise be a treatment for depression?

Chalder M, et al. BMJ 2012; 344:e2758
Recommending structured moderate or vigorous exercise in addition to routine GP care is not effective for the treatment of depression.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1585

Does warming LAs reduce the pain of injection?

Hogan ME, VanderVaart S, Perampaladas K, et al. Ann Emerg Med 2011 Jul; 58(1): 86-98.e1
Warming the local anaesthetic probably does reduce pain in general, but not by much in most individuals.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1582

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