Tag: Medical Observer

Jul 10

Pelargonium sidoides extract (Kaloba (R)) for the common cold

Timmer et al. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No .: CD006323.
There exists only very-low quality evidence of the effect of Pelargonium sidoides extract on the common cold.

May 15

Paracetamol for acute low-back pain

Williams et al. Lancet 2014;384(9954):1586-96.
Paracetamol does not have an effect on time to recovery for acute low-back pain in the general practice setting.

Mar 13

Yoghurt to prevent antibiotic-associated diarrhoea in children

Fox MJ, et al. BMJ Open 2015;5(1): e006474
Probiotic yoghurt appears to reduce the incidence of diarrhoea in children receiving antibiotics in general practice settings.

Nov 07

St John’s wort for minor depression

Rapaport MH, et al. Journal of Psychiatric Research 2011; 45(7): 931-941
St John’s wort is probably ineffective for minor depression.

Sep 05

Does caffeine help with migraines?

Derry et al. Cochrane Database of Syst Rev 2012, Issue 3. Art. No.: CD009281
Oral caffeine as a single dose may have a modest effect on acute pain when used as an adjuvant to oral analgesia.

Jul 11

Echinacea and the common cold in children

Taylor JA, et al. JAMA 2003; 290(21): 2824-30
Echinacea does not appear to be an effective treatment for the common cold in children.

May 16

Newer oral contraceptives and risk of venous thrombosis

de Bastos M, et al. Cochrane Database of Syst Rev 2014, Issue 3. Art. No.: CD010813
cOCPs containing drospirenone as compared to levonorgestrel are associated with twice the risk of venous thrombosis.

Mar 14

Mediterranean diets in type 2 diabetes

Ajala O, et al. Am J Clin Nutr 2013; 97(3): 505-516
The Mediterranean diet appears to be as good as other diets at improving glycaemic control in patients with type 2 diabetes.

Nov 08

Are statins effective for primary prevention in people with low cardiovascular risk?

Tonelli M, et al. CMAJ 2011; 183(16): E1189-E1202
Statins appear to have a (small) cardiovascular benefit, even in individuals at low CVD risk.

Sep 06

Is folate effective for methotrexate side effects?

Shea B, et al. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD000951
Low dose folic acid (≤ 7 mg/week) substantially reduces the likelihood of certain side-effects of methotrexate in patients with rheumatoid arthritis.