Category: Systematic review

Mar 14

Mediterranean diets in type 2 diabetes

Ajala O, et al. Am J Clin Nutr 2013; 97(3): 505-516
The Mediterranean diet appears to be as good as other diets at improving glycaemic control in patients with type 2 diabetes.

Nov 08

Are statins effective for primary prevention in people with low cardiovascular risk?

Tonelli M, et al. CMAJ 2011; 183(16): E1189-E1202
Statins appear to have a (small) cardiovascular benefit, even in individuals at low CVD risk.

Sep 06

Is folate effective for methotrexate side effects?

Shea B, et al. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD000951
Low dose folic acid (≤ 7 mg/week) substantially reduces the likelihood of certain side-effects of methotrexate in patients with rheumatoid arthritis.

Jul 12

Does zinc reduce the symptoms of the common cold?

Science M, Johnstone J, Roth DE, Guyatt G, Loeb M. CMAJ 2012; 184(10): E551-E561
Oral zinc reduces the duration of cold symptoms in adults, but at the cost of side-effects.

Nov 23

Is glucosamine effective for osteoarthritis pain?

Wandel S, Jüni P, Tendal B, et al. BMJ 2010; 341: c4675
Glucosamine does not appear to be effective for knee or hip osteoarthritis pain.

Aug 03

Does warming LAs reduce the pain of injection?

Hogan ME, VanderVaart S, Perampaladas K, et al. Ann Emerg Med 2011 Jul; 58(1): 86-98.e1
Warming the local anaesthetic probably does reduce pain in general, but not by much in most individuals.

Apr 13

Is vitamin C effective in treating the common cold?

Hemilä H, Chalker E, Douglas B. Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD000980.
Oral vitamin C is not an effective treatment for the common cold in the general community.

Dec 09

How can we treat hangovers?

Pittler MH, Verster JC, Ernst E. BMJ 2005; 331: 1515
There is no convincing evidence of the effectiveness of any hangover treatments.

Apr 27

Zinc for the common cold

Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD001364
Zinc administered within 24 hours of the symptoms of a common cold is associated with favourable outcomes but with some side-effects.

Apr 06

Deaths after chiropractic upper cervical spine manipulation

Ernst E. Deaths after chiropractic: a review of published cases. Int J Clin Pract, July 2010; 64(8): 1162-5
Chiropractic, specifically, high-velocity, short-lever thrusts of the upper spine with rotation is associated with numerous deaths.