Category: Rheumatology

Is folate effective for methotrexate side effects?

Shea B, et al. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD000951
Low dose folic acid (≤ 7 mg/week) substantially reduces the likelihood of certain side-effects of methotrexate in patients with rheumatoid arthritis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1603

Is glucosamine effective for osteoarthritis pain?

Wandel S, Jüni P, Tendal B, et al. BMJ 2010; 341: c4675
Glucosamine does not appear to be effective for knee or hip osteoarthritis pain.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1588

Osteoporosis in older men: the CHAMP study

Bleicher K, et al. Prevalence and treatment of osteoporosis in older Australian men: findings from the CHAMP study. MJA 2010;193:387-391
Osteoporosis is very common in men aged over 70 years and probably under-recognised and undertreated; 25% of participants had osteoporosis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=228

Cardiovascular safety of NSAIDs

Trelle S, et al. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ 2011; 342:c7086
Non-steroidal anti-inflammatory drugs (NSAIDs) appear to be associated with increased cardiovascular risks.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1173

Glucosamine and/or chondroitin for osteoarthritis

Wandel S, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 2010;341:c4675
Glucosamine, chondroitin and their combination do not improve pain or reduce joint space loss in osteoarthritis of the hip or knee.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=270

MLV-related virus in blood samples of patients with CFS

Lo S-C, et al. Detection of MLV-related virus gene sequences in blood of patients with chronic fatigue syndrome and healthy blood donors. PNAS September 7, 2010 vol. 107 no. 36 15874-15879
There appears to be an association between chronic fatigue syndrome and murine leukaemia virus-related virus.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=241

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