Category Archive: Gastroenterology

Dec 05

Milk thistle for chronic hepatitis B

Rambaldi et al. Cochrane database Syst Rev 2007 Oct 17(4):CD003620
Milk thistle products cannot be recommended for chronic hepatitis B. Only limited research evidence of unclear/poor quality exists.

Mar 13

Yoghurt to prevent antibiotic-associated diarrhoea in children

Fox MJ, et al. BMJ Open 2015;5(1): e006474
Probiotic yoghurt appears to reduce the incidence of diarrhoea in children receiving antibiotics in general practice settings.

May 24

Is yoghurt helpful for antibiotic-associated diarrhoea?

Conway S, Hart A, Clark A, Harvey I. BJGP 2007; 57(545): 953-959
Yoghurt eaters in this study might have suffered less antibiotic-associated diarrhoea as compared to those who ate no yoghurt.

Apr 13

Proton pump inhibitors with clopidogrel

van Boxel OS, et al. Cardiovascular and gastrointestinal outcomes in clopidogrel users on proton pump inhibitors: results of a large Dutch cohort study. Am J Gastroenterol 2010; 105: 2430–6
Concurrent proton pump inhibitors may increase the risk of cardiovascular outcomes in patients taking clopidogrel.

Jan 14

Placebos for irritable bowel syndrome

Kaptchuk TJ, et al. Placebos without deception: a randomized controlled trial in irritable bowel syndrome. PLoS ONE 2010; 5(12): e15591
The positive results widely reported for placebo pills in consenting patients with irritable bowel syndrome are likely invalid due to serious methodological limitations in the study.