Apr 13 2011
van Boxel OS, et al. Cardiovascular and gastrointestinal outcomes in clopidogrel users on proton pump inhibitors: results of a large Dutch cohort study. Am J Gastroenterol 2010; 105: 2430–6
Concurrent proton pump inhibitors may increase the risk of cardiovascular outcomes in patients taking clopidogrel.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1322
Mar 04 2011
Pasternak B, Hviid A. Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects. JAMA 2010;304(8):859-866
No association was found between the use of aciclovir (Zovirax), or valaciclovir (Valtrex), in early pregnancy and major birth defects.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1046
Feb 25 2011
Gopinath B, et al. Five-year incidence and progression of thyroid dysfunction in an older population. Internal Medicine Journal 2010;40(9):642–649
The rate of progression from subclinical to overt hypothyroidism in older people is about 1 in 6 over five years.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=182
Feb 21 2011
Eick AA, et al. Maternal influenza vaccination and effect on influenza virus infection in young infants. Arch Pediatr Adolesc Med. 2010;0(2010):archpediatrics.2010.192
Maternal influenza vaccination during pregnancy has a limited effect on infant influenza-like illness.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=542
Feb 07 2011
van Nieuwkoop C, et al. Predicting the need for radiologic imaging in adults with febrile urinary tract infection. CID 2010;51(11):1266–1272
A simple clinical prediction rule may predict patients with febrile urinary tract infection who would not benefit from radiologic imaging.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=363
Jan 21 2011
Di Angelantonio E, et al. CKD and risk of major CVD and no-vascular mortality: prospective population based cohort study. BMJ. 2010;341:c4986
Even the earliest stages of CKD seem to be independently associated with an increased risk of subsequent CHD.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=262
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