Feb 14 2011
Athyros VG, et al. Safety and efficacy of long-term statin treatment for cardiovascular events in patients with CHD and abnormal LFTs in GREACE Study: a post-hoc analysis. Lancet 2010; 376: 1916–22
Statin are effective and safe in patients with established coronary heart disease but with mild-to-moderate abnormal liver function tests.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=686
Feb 07 2011
Tähtinen PA, et al. A placebo-controlled trial of antimicrobial treatment for acute otitis media. N Engl J Med 2011; 364: 116-26
Children aged 6-35 months with acute otitis media may benefit from amoxicillin-clavulanate but at the cost of adverse events.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1065
Feb 02 2011
Matchar DB, et al. Effect of home testing of INR on clinical events. N Engl J Med 2010;363:1608-20
Home INR self-testing does not appear to improve or worsen strokes, major bleeds or death when compared to high quality practice based management of anticoagulation.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=282
Jan 31 2011
Bruggink SC, et al. Cryotherapy with liquid nitrogen versus topical salicylic acid application for cutaneous warts in primary care: a randomized controlled trial. CMAJ. October 19, 2010; 182 (15)
Cryotherapy with liquid nitrogen is more effective than topical salicylic acid ointment for treatment of cutaneous common warts.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=807
Jan 14 2011
Kaptchuk TJ, et al. Placebos without deception: a randomized controlled trial in irritable bowel syndrome. PLoS ONE 2010; 5(12): e15591
The positive results widely reported for placebo pills in consenting patients with irritable bowel syndrome are likely invalid due to serious methodological limitations in the study.
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=749
Jan 12 2011
Zoungas S, et al. Severe hypoglycemia and risk of vascular events and death. N Engl J Med 2010;363:1410-8
Severe hypoglycaemia is strongly associated with increased risk of vascular events and death (~ 350% ↑ risk).
Permanent link to this article: https://evidencebasedmedicine.com.au/?p=206
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