Tag Archive: statins

Aug 08

Does co-enzyme Q10 reduce statin-related muscle pain?

Banach et al. Mayo Clin Proc 2015 Jan;90(1):24-34.
The effect of CoQ10 on muscle pain in people on statin therapy is uncertain with the evidence limited and inconsistent. CoQ10 cannot be recommended as a matter of routine supplementation to prevent muscle pain in people taking statins.

Nov 08

Are statins effective for primary prevention in people with low cardiovascular risk?

Tonelli M, et al. CMAJ 2011; 183(16): E1189-E1202
Statins appear to have a (small) cardiovascular benefit, even in individuals at low CVD risk.

Apr 20

Statins in primary prevention and all-cause mortality

Ray KK, et al. Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 RCTs… Archives of Internal Medicine, 2010; 170(12): 1024-31 Statins were not associated with a benefit to all-cause mortality in a primary prevention setting.

Feb 14

Statins, coronary heart disease and abnormal LFTs

Athyros VG, et al. Safety and efficacy of long-term statin treatment for cardiovascular events in patients with CHD and abnormal LFTs in GREACE Study: a post-hoc analysis. Lancet 2010; 376: 1916–22
Statin are effective and safe in patients with established coronary heart disease but with mild-to-moderate abnormal liver function tests.