Tag Archive: NSAID

Jul 03

Should PPIs be routinely co-prescribed with long-term NSAIDs?

Rostom et al. Cochrane database of systematic reviews 2002(4):CD002296.
Proton-pump inhibitors (PPIs) protect against the development of ulcers seen on endoscopy, in patients taking longer-term NSAIDs. Little data exists on clinical outcomes.

Jun 09

NSAIDs as treatment for uncomplicated urinary tract infections

Gagyor et al. BMJ 2015 Dec 23;351:h6544.
NSAIDs should not be recommended as a first line treatment for uncomplicated UTIs in women. Compared to empirical antibiotics, women experienced a significantly greater burden of UTI symptoms.

Mar 07

Cardiovascular safety of NSAIDs

Trelle S, et al. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ 2011; 342:c7086
Non-steroidal anti-inflammatory drugs (NSAIDs) appear to be associated with increased cardiovascular risks.