Tag: Cochrane

Jul 03

Should PPIs be routinely co-prescribed with long-term NSAIDs?

Rostom et al. Cochrane database of systematic reviews 2002(4):CD002296.
Proton-pump inhibitors (PPIs) protect against the development of ulcers seen on endoscopy, in patients taking longer-term NSAIDs. Little data exists on clinical outcomes.

Jul 10

Pelargonium sidoides extract (Kaloba (R)) for the common cold

Timmer et al. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No .: CD006323.
There exists only very-low quality evidence of the effect of Pelargonium sidoides extract on the common cold.

Sep 05

Does caffeine help with migraines?

Derry et al. Cochrane Database of Syst Rev 2012, Issue 3. Art. No.: CD009281
Oral caffeine as a single dose may have a modest effect on acute pain when used as an adjuvant to oral analgesia.

May 16

Newer oral contraceptives and risk of venous thrombosis

de Bastos M, et al. Cochrane Database of Syst Rev 2014, Issue 3. Art. No.: CD010813
cOCPs containing drospirenone as compared to levonorgestrel are associated with twice the risk of venous thrombosis.

Sep 06

Is folate effective for methotrexate side effects?

Shea B, et al. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD000951
Low dose folic acid (≤ 7 mg/week) substantially reduces the likelihood of certain side-effects of methotrexate in patients with rheumatoid arthritis.

Apr 13

Is vitamin C effective in treating the common cold?

Hemilä H, Chalker E, Douglas B. Cochrane Database of Systematic Reviews 2007, Issue 3. Art. No.: CD000980.
Oral vitamin C is not an effective treatment for the common cold in the general community.

Apr 27

Zinc for the common cold

Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD001364
Zinc administered within 24 hours of the symptoms of a common cold is associated with favourable outcomes but with some side-effects.