Rajaraman P, et al. Early life exposure to diagnostic radiation and ultrasound scans and risk of childhood cancer… BMJ 2011; 342: d472
The excess risk of childhood cancer from diagnostic imaging in utero and early infancy remains unclear.
Mar
30
Diagnostic x-ray and ultrasound and childhood cancer
by Michael Tam
Mar
18
Blood pressure measurement; conventional vs automated
by Michael Tam
Myers MG, et al. Conventional versus automated measurement of blood pressure in primary care patients with systolic hypertension: randomised parallel design controlled trial. BMJ 2011; 342: d286
Automated BP measurement is significantly closer to waking ambulatory BP than conventional manual measurement.
Mar
14
Conventional CPR vs chest compression only
by Michael Tam
Ogawa T, et al. Outcomes of chest compression only CPR versus conventional CPR conducted by lay people… BMJ 2011; 342: c7106
Conventional CPR may be associated with better rates of survival than chest compression only CPR when conducted by lay people in out of hospital arrests.
Mar
07
Cardiovascular safety of NSAIDs
by Michael Tam
Trelle S, et al. Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. BMJ 2011; 342:c7086
Non-steroidal anti-inflammatory drugs (NSAIDs) appear to be associated with increased cardiovascular risks.
Feb
28
B-vitamins and omega-3 fatty acids on vascular disease
by Michael Tam
Galan P, et al. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a RCT. BMJ 2010; 341:c6273
B-vitamin and low dose omega-3 fatty acid supplements are not associated with better vascular outcomes in people with ischaemic heart disease and stroke.
Feb
23
Antipsychotics and the risk of venous thromboembolism
by Michael Tam
Parker C, Coupland C, Hippisley-Cox J. Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ 2010;341:c4245.
Antipsychotic drugs are associated with a 32% increased risk of venous thromboembolism.
Feb
04
PSA at age 60 and death or metastasis from prostate cancer
by Michael Tam
Vickers AJ, et al. PSA concentration at age 60 and death or metastasis from prostate cancer: case-control study. BMJ 2010;341:c4521
Men aged 60 years with a PSA < 1.0 ng/mL have less than a 0.5% risk of prostate cancer metastasis or prostate cancer death by age 85.
Jan
28
Glucosamine and/or chondroitin for osteoarthritis
by Michael Tam
Wandel S, et al. Effects of glucosamine, chondroitin, or placebo in patients with osteoarthritis of hip or knee: network meta-analysis. BMJ 2010;341:c4675
Glucosamine, chondroitin and their combination do not improve pain or reduce joint space loss in osteoarthritis of the hip or knee.
Jan
21
Chronic kidney disease and risk of cardiovascular disease
by Michael Tam
Di Angelantonio E, et al. CKD and risk of major CVD and no-vascular mortality: prospective population based cohort study. BMJ. 2010;341:c4986
Even the earliest stages of CKD seem to be independently associated with an increased risk of subsequent CHD.
Jan
19
Reboxetine for acute treatment of major depression
by Michael Tam
Eyding D, et al. Reboxetine for acute treatment of major depression: systematic review and meta-analysis of published and unpublished placebo and SSRI. BMJ 2010;341:c4737
Reboxetine is no more effective than placebo for major depressive disorder.