Category: Cardiology

Feb 28

B-vitamins and omega-3 fatty acids on vascular disease

Galan P, et al. Effects of B vitamins and omega 3 fatty acids on cardiovascular diseases: a RCT. BMJ 2010; 341:c6273
B-vitamin and low dose omega-3 fatty acid supplements are not associated with better vascular outcomes in people with ischaemic heart disease and stroke.

Feb 18

Omega-3 fatty acids for prevention of atrial fibrillation

Kowey PR, et al. Efficacy and safety of prescription omega-3 fatty acids for the prevention of recurrent symptomatic atrial fibrillation. JAMA 2010; 304(21): 2363-72
High dose omega-3 fatty acids were not associated with a benefit in prevention of recurrent symptomatic AF.

Feb 16

Daily aspirin on long-term risk of death due to cancer

Rothwell PM, et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011; 377(9759): 31-41
Daily aspirin (≥ 75 mg) taken by participants in cardiovascular studies reduced the risk of cancer death.

Feb 14

Statins, coronary heart disease and abnormal LFTs

Athyros VG, et al. Safety and efficacy of long-term statin treatment for cardiovascular events in patients with CHD and abnormal LFTs in GREACE Study: a post-hoc analysis. Lancet 2010; 376: 1916–22
Statin are effective and safe in patients with established coronary heart disease but with mild-to-moderate abnormal liver function tests.

Jan 21

Chronic kidney disease and risk of cardiovascular disease

Di Angelantonio E, et al. CKD and risk of major CVD and no-vascular mortality: prospective population based cohort study. BMJ. 2010;341:c4986
Even the earliest stages of CKD seem to be independently associated with an increased risk of subsequent CHD.

Jan 12

Severe hypoglycemia and risk of vascular events and death

Zoungas S, et al. Severe hypoglycemia and risk of vascular events and death. N Engl J Med 2010;363:1410-8
Severe hypoglycaemia is strongly associated with increased risk of vascular events and death (~ 350% ↑ risk).

Jan 05

Subclinical hypothyroidism and coronary heart disease

Rondondi N, et al. Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA. 2010;304(12):1365-1374.
Subclinical hypothyroidism (elevated TSH with normal thyroxine levels) is associated with increased risk of coronary heart disease (CHD) events and mortality.