Category: Paediatrics

Do oral sweets reduce injection pain in children?

Harrison et al. Cochrane database of systematic reviews 2015 May 5(5):CD008408
The effect of oral sweets on injection pain in children is unclear. Much of the data were from small studies with conflicting results. There is better evidence for other approaches (e.g., distraction).

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1733

Yoghurt to prevent antibiotic-associated diarrhoea in children

Fox MJ, et al. BMJ Open 2015;5(1): e006474
Probiotic yoghurt appears to reduce the incidence of diarrhoea in children receiving antibiotics in general practice settings.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1658

Echinacea and the common cold in children

Taylor JA, et al. JAMA 2003; 290(21): 2824-30
Echinacea does not appear to be an effective treatment for the common cold in children.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1638

Antibiotic drops for conjunctivitis in children

Rose PW, Harnden A, Brueggemann AB, et al. Lancet 2005; 366(9479): 37-43
The majority of children are cured by day 7 regardless of treatment.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1577

Inhaled corticosteroids as rescue treatment

Martinez FD, et al. Use of beclomethasone dipropionate as rescue treatment for mild persistent asthma…. Lancet 2011; 377: 650–57
Inhaled beclomethasone (Qvar) used as rescue therapy with salbutamol is likely better than salbutamol alone, for children with mild persistent asthma who do not take regular inhaled corticosteroids.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1420

Diagnostic x-ray and ultrasound and childhood cancer

Rajaraman P, et al. Early life exposure to diagnostic radiation and ultrasound scans and risk of childhood cancer… BMJ 2011; 342: d472
The excess risk of childhood cancer from diagnostic imaging in utero and early infancy remains unclear.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1295

Antiherpetic antivirals in pregnancy and birth defects

Pasternak B, Hviid A. Use of acyclovir, valacyclovir, and famciclovir in the first trimester of pregnancy and the risk of birth defects. JAMA 2010;304(8):859-866
No association was found between the use of aciclovir (Zovirax), or valaciclovir (Valtrex), in early pregnancy and major birth defects.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1046

DHA on maternal depression and neurodevelopment

Makrides M, et al. Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trial. JAMA. 2010; 304(15): 1675-1683
DHA supplements in the later half of pregnancy are not associated with improvements in maternal depression or infant neurodevelopment.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=989

Maternal flu vaccination and flu infection in young infants

Eick AA, et al. Maternal influenza vaccination and effect on influenza virus infection in young infants. Arch Pediatr Adolesc Med. 2010;0(2010):archpediatrics.2010.192
Maternal influenza vaccination during pregnancy has a limited effect on infant influenza-like illness.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=542

Symptoms and signs of croup and epiglottitis

Tibballs J, Watson T. Symptoms and signs differentiating croup and epiglottitis. Journal of Paediatrics and Child Health. (2010) 10.1111/j.1440-1754.2010.01892.x
Cough and drooling can be helpful in differentiating croup and epiglottitis in children with acute stridor.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=562

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