Category: Oncology

Mar 30

Diagnostic x-ray and ultrasound and childhood cancer

Rajaraman P, et al. Early life exposure to diagnostic radiation and ultrasound scans and risk of childhood cancer… BMJ 2011; 342: d472
The excess risk of childhood cancer from diagnostic imaging in utero and early infancy remains unclear.

Mar 16

HRT and breast cancer incidence and mortality

Chlebowski R, et al. Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA. 2010; 304 (15):1684-1692
Combined oestrogen and progestin HRT is associated with increased risk of invasive breast cancer, node-positivity, and all cause mortality.

Feb 16

Daily aspirin on long-term risk of death due to cancer

Rothwell PM, et al. Effect of daily aspirin on long-term risk of death due to cancer: analysis of individual patient data from randomised trials. Lancet 2011; 377(9759): 31-41
Daily aspirin (≥ 75 mg) taken by participants in cardiovascular studies reduced the risk of cancer death.

Feb 09

Antihypertensive drugs and the risk of cancer

Bangalore S, et al. Antihypertensive drugs and risk of cancer: network meta-analyses and trial sequential analyses of 324,168 participants from randomised trials. Lancet Oncol (2010)
Antihypertensive drugs do not appear to increase cancer risk or cancer-related deaths.

Feb 04

PSA at age 60 and death or metastasis from prostate cancer

Vickers AJ, et al. PSA concentration at age 60 and death or metastasis from prostate cancer: case-control study. BMJ 2010;341:c4521
Men aged 60 years with a PSA < 1.0 ng/mL have less than a 0.5% risk of prostate cancer metastasis or prostate cancer death by age 85.