Category: Meta-analysis

Dec 05

Milk thistle for chronic hepatitis B

Rambaldi et al. Cochrane database Syst Rev 2007 Oct 17(4):CD003620
Milk thistle products cannot be recommended for chronic hepatitis B. Only limited research evidence of unclear/poor quality exists.

Sep 04

Corticosteroid injections for tennis elbow

Olaussen et al. BMJ Open 2013;3(10):e003564
Corticosteroid injections should generally be avoided for tennis elbow (lateral epicondylitis).

Jul 10

Pelargonium sidoides extract (Kaloba (R)) for the common cold

Timmer et al. Cochrane Database of Systematic Reviews 2013, Issue 10. Art. No .: CD006323.
There exists only very-low quality evidence of the effect of Pelargonium sidoides extract on the common cold.

Sep 05

Does caffeine help with migraines?

Derry et al. Cochrane Database of Syst Rev 2012, Issue 3. Art. No.: CD009281
Oral caffeine as a single dose may have a modest effect on acute pain when used as an adjuvant to oral analgesia.

May 16

Newer oral contraceptives and risk of venous thrombosis

de Bastos M, et al. Cochrane Database of Syst Rev 2014, Issue 3. Art. No.: CD010813
cOCPs containing drospirenone as compared to levonorgestrel are associated with twice the risk of venous thrombosis.

Apr 16

Diagnostic utility of rheumatoid factor in low risk population

Nishimura K, et al. Ann Intern Med 2007; 146(11): 797-808
There is no role for diagnostic rheumatoid factor (RF) testing in someone without inflammatory arthritis.

Mar 15

Do calcium supplements increase the risk of myocardial infarction?

Bolland M, et al. BMJ 2010; 341: c3691
Calcium supplements may increase the risk of myocardial infarction, but, there is substantial uncertainty in the estimate.

Apr 27

Zinc for the common cold

Singh M, Das RR. Zinc for the common cold. Cochrane Database of Systematic Reviews 2011, Issue 2. Art. No.: CD001364
Zinc administered within 24 hours of the symptoms of a common cold is associated with favourable outcomes but with some side-effects.

Apr 20

Statins in primary prevention and all-cause mortality

Ray KK, et al. Statins and all-cause mortality in high-risk primary prevention: a meta-analysis of 11 RCTs… Archives of Internal Medicine, 2010; 170(12): 1024-31 Statins were not associated with a benefit to all-cause mortality in a primary prevention setting.

Mar 23

Cannabis use and earlier onset of psychosis

Large M, et al. Cannabis use and earlier onset of psychosis. Arch Gen Psychiatry 2011: published online 7 February 2011
Cannabis may be causally related to psychotic illness but the evidence remains unclear.