Category Archive: Endocrinology

Aug 31

Do vitamin D supplements reduce falls in older people living in the community?

Bolland et al. Lancet Diabetes Endocrinol 2014 Jul;2(7):573-80
The beneficial effect of vitamin D on falls in otherwise well community-dwelling people is likely to be small, if it exists at all. Its routine preventive use cannot be justified on the evidence.

Jun 14

Metformin as prevention in people taking antipsychotic medication

Zheng et al. J Clin Psychopharmacol 2015 Oct;35(5):499-509.
The effect of metformin on cardiovascular disease in people living without diabetes on long-term antipsychotic medication is unknown.

Mar 14

Mediterranean diets in type 2 diabetes

Ajala O, et al. Am J Clin Nutr 2013; 97(3): 505-516
The Mediterranean diet appears to be as good as other diets at improving glycaemic control in patients with type 2 diabetes.

May 11

Type 2 diabetes and increased risk for malaria

Danquah I, et al. Type 2 diabetes mellitus and increased risk for malaria infection. Emerg Inf Dis 2010; 16 (1): 1601-1604
There may be an association between type 2 diabetes and malaria infection.

Mar 21

Osteoporosis in older men: the CHAMP study

Bleicher K, et al. Prevalence and treatment of osteoporosis in older Australian men: findings from the CHAMP study. MJA 2010;193:387-391
Osteoporosis is very common in men aged over 70 years and probably under-recognised and undertreated; 25% of participants had osteoporosis.

Feb 25

Incidence and progression of thyroid dysfunction in elderly

Gopinath B, et al. Five-year incidence and progression of thyroid dysfunction in an older population. Internal Medicine Journal 2010;40(9):642–649
The rate of progression from subclinical to overt hypothyroidism in older people is about 1 in 6 over five years.

Jan 12

Severe hypoglycemia and risk of vascular events and death

Zoungas S, et al. Severe hypoglycemia and risk of vascular events and death. N Engl J Med 2010;363:1410-8
Severe hypoglycaemia is strongly associated with increased risk of vascular events and death (~ 350% ↑ risk).

Jan 05

Subclinical hypothyroidism and coronary heart disease

Rondondi N, et al. Subclinical hypothyroidism and the risk of coronary heart disease and mortality. JAMA. 2010;304(12):1365-1374.
Subclinical hypothyroidism (elevated TSH with normal thyroxine levels) is associated with increased risk of coronary heart disease (CHD) events and mortality.