Category: Rheumatology

Aug 31

Do vitamin D supplements reduce falls in older people living in the community?

Bolland et al. Lancet Diabetes Endocrinol 2014 Jul;2(7):573-80
The beneficial effect of vitamin D on falls in otherwise well community-dwelling people is likely to be small, if it exists at all. Its routine preventive use cannot be justified on the evidence.

Oct 10

Sterile water injections for acute low back pain

Cui JZ, et al. Braz J Med Biol Res 2016 Mar;49(3)
Sterile water injections are of uncertain value in acute low back pain. It may have a role in patients who consent after being informed to its uncertain value.

Aug 08

Does co-enzyme Q10 reduce statin-related muscle pain?

Banach et al. Mayo Clin Proc 2015 Jan;90(1):24-34.
The effect of CoQ10 on muscle pain in people on statin therapy is uncertain with the evidence limited and inconsistent. CoQ10 cannot be recommended as a matter of routine supplementation to prevent muscle pain in people taking statins.

Oct 30

Starting allopurinol in acute gout

Hill et al. J Clin Rheumatol 2015;21(3):120-5.
It is unclear what effect starting allopurinol in acute has on symptoms, due to the lack of good evidence. It may be preferable to avoid starting allopurinol in an acute attack, but this should not be a dogmatic stance.

Sep 04

Corticosteroid injections for tennis elbow

Olaussen et al. BMJ Open 2013;3(10):e003564
Corticosteroid injections should generally be avoided for tennis elbow (lateral epicondylitis).

May 15

Paracetamol for acute low-back pain

Williams et al. Lancet 2014;384(9954):1586-96.
Paracetamol does not have an effect on time to recovery for acute low-back pain in the general practice setting.

Apr 16

Diagnostic utility of rheumatoid factor in low risk population

Nishimura K, et al. Ann Intern Med 2007; 146(11): 797-808
There is no role for diagnostic rheumatoid factor (RF) testing in someone without inflammatory arthritis.

Sep 06

Is folate effective for methotrexate side effects?

Shea B, et al. Cochrane Database of Systematic Reviews 2013, Issue 5. Art. No.: CD000951
Low dose folic acid (≤ 7 mg/week) substantially reduces the likelihood of certain side-effects of methotrexate in patients with rheumatoid arthritis.

Nov 23

Is glucosamine effective for osteoarthritis pain?

Wandel S, Jüni P, Tendal B, et al. BMJ 2010; 341: c4675
Glucosamine does not appear to be effective for knee or hip osteoarthritis pain.

Mar 21

Osteoporosis in older men: the CHAMP study

Bleicher K, et al. Prevalence and treatment of osteoporosis in older Australian men: findings from the CHAMP study. MJA 2010;193:387-391
Osteoporosis is very common in men aged over 70 years and probably under-recognised and undertreated; 25% of participants had osteoporosis.