Category Archive: Randomised controlled trial

May 15

Paracetamol for acute low-back pain

Williams et al. Lancet 2014;384(9954):1586-96.
Paracetamol does not have an effect on time to recovery for acute low-back pain in the general practice setting.

Mar 13

Yoghurt to prevent antibiotic-associated diarrhoea in children

Fox MJ, et al. BMJ Open 2015;5(1): e006474
Probiotic yoghurt appears to reduce the incidence of diarrhoea in children receiving antibiotics in general practice settings.

Nov 07

St John’s wort for minor depression

Rapaport MH, et al. Journal of Psychiatric Research 2011; 45(7): 931-941
St John’s wort is probably ineffective for minor depression.

Jul 11

Echinacea and the common cold in children

Taylor JA, et al. JAMA 2003; 290(21): 2824-30
Echinacea does not appear to be an effective treatment for the common cold in children.

May 24

Is yoghurt helpful for antibiotic-associated diarrhoea?

Conway S, Hart A, Clark A, Harvey I. BJGP 2007; 57(545): 953-959
Yoghurt eaters in this study might have suffered less antibiotic-associated diarrhoea as compared to those who ate no yoghurt.

Sep 28

Can exercise be a treatment for depression?

Chalder M, et al. BMJ 2012; 344:e2758
Recommending structured moderate or vigorous exercise in addition to routine GP care is not effective for the treatment of depression.

Jun 08

Antibiotic drops for conjunctivitis in children

Rose PW, Harnden A, Brueggemann AB, et al. Lancet 2005; 366(9479): 37-43
The majority of children are cured by day 7 regardless of treatment.

Oct 24

Is cryotherapy the best treatment for common warts?

Bruggink SC, et al. CMAJ 2010; 182(15): 1624-30
LN2 cryotherapy is likely more effective than topical salicyclic acid for the treatment of common warts in primary care.

Aug 19

Can cranberry prevent UTIs?

Barbosa-Cesnik C, et al. Cranberry juice fails to prevent recurrent urinary tract infection: results from a randomised placebo-controlled trial. Clinical Infectious Diseases 2011; 52(1): 23-30
Cranberry juice is unlikely to be an effective prophylactic for recurrent urinary tract infections in young women.

Jun 22

Dabigatran versus warfarin for atrial fibrillation

Connolly SJ, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361:1139-1151
Dabigatran (Pradaxa) is non-inferior to warfarin for the prevention of strokes or systemic embolism, in non-valvular atrial fibrillation.

Older posts «

» Newer posts