Category: Gynaecology

Newer oral contraceptives and risk of venous thrombosis

de Bastos M, et al. Cochrane Database of Syst Rev 2014, Issue 3. Art. No.: CD010813
cOCPs containing drospirenone as compared to levonorgestrel are associated with twice the risk of venous thrombosis.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1615

HRT and breast cancer incidence and mortality

Chlebowski R, et al. Estrogen plus progestin and breast cancer incidence and mortality in postmenopausal women. JAMA. 2010; 304 (15):1684-1692
Combined oestrogen and progestin HRT is associated with increased risk of invasive breast cancer, node-positivity, and all cause mortality.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1062

Escitalopram for hot flushes in menopausal women

Freeman EW, et al. Efficacy of escitalopram for hot flashes in healthy menopausal women: a randomized controlled trial. JAMA. 2001; 305(3): 267-74
Escitalopram is probably associated with a mild improvement in the frequency and severity of hot flushes in peri-menopausal women.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1075