Category: Haematology

Feb 19 2016

Aspirin as DVT prophylaxis for high risk long-haul travellers

Cesarone MR, et al. Angiology 2002 Jan-Feb;53(1):1-6.
It is unclear whether aspirin is effective as DVT prophylaxis for high risk long-haul travellers. The lack of evidence should preclude it from being recommended.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1687

Jun 22 2011

Dabigatran versus warfarin for atrial fibrillation

Connolly SJ, et al. Dabigatran versus warfarin in patients with atrial fibrillation. N Engl J Med 2009; 361:1139-1151
Dabigatran (Pradaxa) is non-inferior to warfarin for the prevention of strokes or systemic embolism, in non-valvular atrial fibrillation.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1443

Apr 13 2011

Proton pump inhibitors with clopidogrel

van Boxel OS, et al. Cardiovascular and gastrointestinal outcomes in clopidogrel users on proton pump inhibitors: results of a large Dutch cohort study. Am J Gastroenterol 2010; 105: 2430–6
Concurrent proton pump inhibitors may increase the risk of cardiovascular outcomes in patients taking clopidogrel.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1322

Feb 23 2011

Antipsychotics and the risk of venous thromboembolism

Parker C, Coupland C, Hippisley-Cox J. Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ 2010;341:c4245.
Antipsychotic drugs are associated with a 32% increased risk of venous thromboembolism.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=191

Feb 02 2011

Effect of home testing of INR on clinical events

Matchar DB, et al. Effect of home testing of INR on clinical events. N Engl J Med 2010;363:1608-20
Home INR self-testing does not appear to improve or worsen strokes, major bleeds or death when compared to high quality practice based management of anticoagulation.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=282