Category: Psychiatry

Mar 11 2019

EMDR as treatment for post-traumatic stress disorder

Bisson et al. Cochrane database of systematic reviews 2013 Dec 13(12):CD003388
Eye movement desensitisation and reprocessing (EMDR) appears to be effective for post-traumatic stress disorder (PTSD) symptoms.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1762

Jun 25 2018

Do statins prevent dementia?

McGuinness et al. Cochrane database of systematic reviews 2016 Jan 4(1):CD003160
Statins should not be used as a prophylaxis against dementia, as the only indication. The limited evidence from high quality randomised trials suggests no effect.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1742

Nov 06 2017

Baclofen as treatment for alcohol use disorders

Garbutt et al. Alcohol Clin Exp Res 2010 Nov;34(11):1849-57
Baclofen cannot be recommended as a routine treatment for alcohol use disorders. The quality of the evidence is low overall.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1728

Jun 14 2016

Metformin as prevention in people taking antipsychotic medication

Zheng et al. J Clin Psychopharmacol 2015 Oct;35(5):499-509.
The effect of metformin on cardiovascular disease in people living without diabetes on long-term antipsychotic medication is unknown.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1693

Nov 07 2014

St John’s wort for minor depression

Rapaport MH, et al. Journal of Psychiatric Research 2011; 45(7): 931-941
St John’s wort is probably ineffective for minor depression.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1654

Sep 28 2012

Can exercise be a treatment for depression?

Chalder M, et al. BMJ 2012; 344:e2758
Recommending structured moderate or vigorous exercise in addition to routine GP care is not effective for the treatment of depression.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1585

Mar 23 2011

Cannabis use and earlier onset of psychosis

Large M, et al. Cannabis use and earlier onset of psychosis. Arch Gen Psychiatry 2011: published online 7 February 2011
Cannabis may be causally related to psychotic illness but the evidence remains unclear.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=1280

Mar 02 2011

DHA on maternal depression and neurodevelopment

Makrides M, et al. Effect of DHA supplementation during pregnancy on maternal depression and neurodevelopment of young children: a randomized controlled trial. JAMA. 2010; 304(15): 1675-1683
DHA supplements in the later half of pregnancy are not associated with improvements in maternal depression or infant neurodevelopment.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=989

Feb 23 2011

Antipsychotics and the risk of venous thromboembolism

Parker C, Coupland C, Hippisley-Cox J. Antipsychotic drugs and risk of venous thromboembolism: nested case-control study. BMJ 2010;341:c4245.
Antipsychotic drugs are associated with a 32% increased risk of venous thromboembolism.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=191

Jan 19 2011

Reboxetine for acute treatment of major depression

Eyding D, et al. Reboxetine for acute treatment of major depression: systematic review and meta-analysis of published and unpublished placebo and SSRI. BMJ 2010;341:c4737
Reboxetine is no more effective than placebo for major depressive disorder.

Permanent link to this article: https://evidencebasedmedicine.com.au/?p=250